Long-Term Evolution Experiment
GPTKB entity
Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
scientific research
|
| gptkbp:affiliatedWith |
gptkb:Michigan_State_University
|
| gptkbp:availableOn |
open data policy
|
| gptkbp:citation |
highly cited in evolutionary biology
|
| gptkbp:duration |
over 75,000 generations (as of 2024)
|
| gptkbp:fundedBy |
gptkb:National_Institutes_of_Health
gptkb:National_Science_Foundation |
| https://www.w3.org/2000/01/rdf-schema#label |
Long-Term Evolution Experiment
|
| gptkbp:impact |
advanced understanding of adaptation
demonstrated long-term adaptation influenced experimental evolution research provided insights into mutation rates studied clonal interference studied epistasis studied fitness landscapes studied genetic drift studied genome evolution studied historical contingency studied metabolic evolution studied parallel evolution studied pleiotropy studied trade-offs in adaptation |
| gptkbp:launched |
gptkb:Richard_Lenski
|
| gptkbp:location |
gptkb:Michigan_State_University
|
| gptkbp:mediaCoverage |
featured in Nature, Science, New York Times
|
| gptkbp:medium |
minimal glucose medium
|
| gptkbp:method |
daily transfer of bacteria to fresh medium
|
| gptkbp:mutationAssociatedWith |
citT gene duplication
mutT gene mutations rpoS gene mutations |
| gptkbp:notableAchievement |
documented increased fitness over time
studied genetic and phenotypic changes demonstrated reproducibility and contingency in evolution |
| gptkbp:notableAlumni |
gptkb:Jeffrey_Barrick
gptkb:Neerja_Hajela gptkb:Zachary_Blount |
| gptkbp:notableFinds |
evolution of citrate metabolism in E. coli
|
| gptkbp:numberOfPopulations |
12
|
| gptkbp:organism |
gptkb:Bacteria
|
| gptkbp:principalInvestigator |
gptkb:Richard_Lenski
|
| gptkbp:publishedIn |
multiple peer-reviewed articles
|
| gptkbp:purpose |
study evolution in real time
|
| gptkbp:relatedTo |
experimental evolution
evolutionary dynamics microbial evolution |
| gptkbp:sampleInterval |
every 500 generations
|
| gptkbp:startDate |
February 24, 1988
|
| gptkbp:storage |
frozen samples at regular intervals
|
| gptkbp:website |
https://lenski.mmg.msu.edu/ltee/
|
| gptkbp:bfsParent |
gptkb:Richard_Lenski
|
| gptkbp:bfsLayer |
5
|