Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:appointed_by |
injection
oral tablet |
| gptkbp:approves |
gptkb:1962
gptkb:FDA |
| gptkbp:brand |
gptkb:Fusilev
gptkb:Wellcovorin |
| gptkbp:class |
antidote
chemoprotective agent |
| gptkbp:clinical_trial |
support in high-dose methotrexate therapy
use in acute lymphoblastic leukemia use in colorectal cancer use in non-Hodgkin lymphoma use in osteosarcoma |
| gptkbp:contraindication |
severe renal impairment
hypersensitivity to leucovorin |
| gptkbp:dosage_form |
gptkb:tablet
varies by condition injection solution |
| gptkbp:excretion |
urine
|
| gptkbp:formulation |
calcium salt
|
| https://www.w3.org/2000/01/rdf-schema#label |
Leucovorin Calcium
|
| gptkbp:ingredients |
C20 H22 N8 O7 S
|
| gptkbp:interacts_with |
gptkb:methotrexate
gptkb:phenytoin sulfasalazine |
| gptkbp:is_available_on |
generic drug
brand name drug |
| gptkbp:is_used_for |
chemotherapy support
treatment of folate deficiency |
| gptkbp:manager |
oral
intravenous |
| gptkbp:metabolism |
liver
|
| gptkbp:related_to |
gptkb:methotrexate
gptkb:healthcare_organization folic acid |
| gptkbp:side_effect |
gptkb:fandom
dizziness fatigue headache nausea allergic reactions diarrhea rash |
| gptkbp:storage |
room temperature
protected from light |
| gptkbp:type_of |
1492-18-8
|
| gptkbp:bfsParent |
gptkb:leucovorin
|
| gptkbp:bfsLayer |
5
|