Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
epileptic syndrome
|
| gptkbp:alsoKnownAs |
gptkb:Lennox-Gastaut_syndrome
|
| gptkbp:associatedWith |
intellectual disability
behavioral problems refractory seizures |
| gptkbp:characterizedBy |
cognitive impairment
multiple seizure types slow spike-and-wave EEG pattern |
| gptkbp:complication |
status epilepticus
developmental delay injuries from falls |
| gptkbp:diagnosedBy |
gptkb:EEG
neuroimaging clinical evaluation |
| gptkbp:EEGPattern |
slow spike-and-wave discharges
paroxysmal fast activity during sleep |
| gptkbp:firstDescribed |
1966
Henri Gastaut William G. Lennox |
| gptkbp:gender |
more common in males
|
| gptkbp:hasGeneticCause |
rarely identified
|
| https://www.w3.org/2000/01/rdf-schema#label |
Lennox-Gastaut Epilepsy
|
| gptkbp:ICD-10_code |
G40.4
|
| gptkbp:longTermOutcome |
persistent seizures into adulthood
|
| gptkbp:mortalityRate |
higher than general epilepsy population
|
| gptkbp:onset |
childhood
between 3 and 5 years |
| gptkbp:prevalence |
rare
1-2% of all childhood epilepsies |
| gptkbp:prognosis |
often poor
|
| gptkbp:progression |
can evolve from West syndrome
|
| gptkbp:relatedTo |
gptkb:Dravet_syndrome
West syndrome childhood epileptic encephalopathies |
| gptkbp:riskFactor |
gptkb:tuberous_sclerosis
genetic disorders brain injury perinatal asphyxia CNS infections |
| gptkbp:seizureType |
atonic seizures
myoclonic seizures generalized tonic-clonic seizures atypical absence seizures tonic seizures |
| gptkbp:treatment |
gptkb:ketogenic_diet
gptkb:vagus_nerve_stimulation gptkb:corpus_callosotomy antiepileptic drugs |
| gptkbp:bfsParent |
gptkb:D004239
|
| gptkbp:bfsLayer |
8
|