LPL gene

GPTKB entity

Properties (76)
Predicate Object
gptkbp:instanceOf gene
gptkbp:associatedWith lipid metabolism
gptkbp:code gptkb:lipoprotein_lipase
gptkbp:diedIn diabetes
obesity
atherosclerosis
gptkbp:geneticDiversity lipoprotein lipase deficiency
gptkbp:hasRole fasting lipid metabolism
postprandial lipid metabolism
https://www.w3.org/2000/01/rdf-schema#label LPL gene
gptkbp:influences cholesterol levels
plasma triglyceride levels
gptkbp:interactsWith apolipoprotein C-II
apolipoprotein C-III
gptkbp:involvedIn triglyceride hydrolysis
gptkbp:is_evaluated_by adipose tissue
heart
skeletal muscle
gptkbp:isAssociatedWith metabolic syndrome
cardiovascular disease
gptkbp:isInvolvedIn apoptosis
cell differentiation
cell growth
cell signaling
cellular metabolism
energy homeostasis
glucose metabolism
immune response
lipid transport
energy storage
inflammation
amino acid metabolism
urea cycle
insulin sensitivity
energy expenditure
oxidative stress
angiogenesis
neuroprotection
hormonal regulation
cellular signaling pathways
fat storage
fatty acid synthesis
nucleotide metabolism
tissue remodeling
gluconeogenesis
cholesterol synthesis
ketogenesis
lipolysis
lipogenesis
metabolic regulation
muscle repair
cholesterol transport
signal transduction.
mineral metabolism
nutrient sensing
vitamin metabolism
hormone metabolism
neurotransmitter metabolism
fatty acid transport
ketone body metabolism
lipid droplet formation
lipoprotein metabolism
gptkbp:isLinkedTo familial_chylomicronemia
familial_hyperlipoproteinemia
gptkbp:isLocatedIn liver
pancreas
lungs
gptkbp:isPartOf lipid metabolism pathway
gptkbp:isRegulatedBy gptkb:glucagon
insulin
gptkbp:isStudiedIn gene therapy trials
gene knockout models
gptkbp:isTrainedIn gene therapy
gptkbp:isUtilizedFor normal fat metabolism
gptkbp:locatedIn human chromosome 8
gptkbp:regulates fatty acid uptake