Kolbe-Schmitt reaction

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:application pharmaceutical industry
aspirin synthesis
gptkbp:discoveredBy gptkb:Rudolf_Schmitt
gptkb:Adolph_Wilhelm_Hermann_Kolbe
gptkbp:discoveredIn 1860
https://www.w3.org/2000/01/rdf-schema#label Kolbe-Schmitt reaction
gptkbp:mechanismOfAction gptkb:electrophilic_aromatic_substitution
gptkbp:notableFeature industrial production of salicylic acid
ortho-carboxylation of phenol
gptkbp:otherName Kolbe reaction
gptkbp:product gptkb:salicylic_acid
sodium salicylate
gptkbp:reactant carbon dioxide
phenol
sodium hydroxide
gptkbp:reactionCondition high temperature
high pressure
gptkbp:type carboxylation
gptkbp:bfsParent gptkb:Rudolf_Schmitt
gptkbp:bfsLayer 6