Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
analgesic
antipyretic nonsteroidal anti-inflammatory drug propionic acid derivative |
| gptkbp:approvedInUS |
1986
|
| gptkbp:ATCCode |
M01AE03
|
| gptkbp:brand |
Actron
Ketoflam Orudis Oruvail |
| gptkbp:CASNumber |
22071-15-4
|
| gptkbp:chemicalFormula |
C16H14O3
|
| gptkbp:contraindication |
peptic ulcer
hypersensitivity to NSAIDs severe heart failure |
| gptkbp:discoveredBy |
gptkb:Rhône-Poulenc
|
| gptkbp:discoveredIn |
1967
|
| gptkbp:eliminationHalfLife |
2-2.5 hours
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ketoprofen
|
| gptkbp:isomerOf |
racemic mixture
|
| gptkbp:IUPACName |
2-(3-benzoylphenyl)propanoic acid
|
| gptkbp:KEGGID |
D00318
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
COX inhibitor
prostaglandin synthesis inhibitor |
| gptkbp:MedlinePlusID |
a686014
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
254.28 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
3825
CHEMBL686 DB01009 |
| gptkbp:routeOfAdministration |
oral
topical intramuscular intravenous rectal |
| gptkbp:sideEffect |
nausea
dizziness headache rash dyspepsia gastrointestinal upset |
| gptkbp:UNII |
6UFN2M4IK9
|
| gptkbp:usedFor |
fever
pain inflammation |
| gptkbp:bfsParent |
gptkb:Zentiva
|
| gptkbp:bfsLayer |
7
|