|
gptkbp:instanceOf
|
gptkb:analgesic
gptkb:nonsteroidal_anti-inflammatory_drug
gptkb:propionic_acid_derivative
gptkb:antipyretic
|
|
gptkbp:approvedInUS
|
1986
|
|
gptkbp:ATCCode
|
M01AE03
|
|
gptkbp:brand
|
Actron
Ketoflam
Orudis
Oruvail
|
|
gptkbp:CASNumber
|
22071-15-4
|
|
gptkbp:chemicalFormula
|
C16H14O3
|
|
gptkbp:contraindication
|
gptkb:peptic_ulcer
hypersensitivity to NSAIDs
severe heart failure
|
|
gptkbp:discoveredBy
|
gptkb:Rhône-Poulenc
|
|
gptkbp:discoveredIn
|
1967
|
|
gptkbp:eliminationHalfLife
|
2-2.5 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:isomerOf
|
gptkb:racemic_mixture
|
|
gptkbp:IUPACName
|
2-(3-benzoylphenyl)propanoic acid
|
|
gptkbp:KEGGID
|
D00318
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
COX inhibitor
prostaglandin synthesis inhibitor
|
|
gptkbp:MedlinePlusID
|
a686014
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
254.28 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
3825
CHEMBL686
DB01009
|
|
gptkbp:routeOfAdministration
|
oral
topical
intramuscular
intravenous
rectal
|
|
gptkbp:sideEffect
|
nausea
dizziness
headache
rash
dyspepsia
gastrointestinal upset
|
|
gptkbp:UNII
|
6UFN2M4IK9
|
|
gptkbp:usedFor
|
fever
pain
inflammation
|
|
gptkbp:bfsParent
|
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ketoprofen
|