Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:type_I_keratin |
gptkbp:alternativeName |
gptkb:K14
cytokeratin 14 |
gptkbp:discoveredIn |
1980s
|
gptkbp:encodedBy |
gptkb:KRT14_gene
|
gptkbp:expressedIn |
embryonic development
stratified squamous epithelia |
gptkbp:formsHeterodimerWith |
gptkb:Keratin_5
|
gptkbp:formsIntermediateFilamentsWith |
gptkb:Keratin_5
|
gptkbp:foundIn |
epithelial cells
|
gptkbp:function |
mechanical stability of keratinocytes
|
https://www.w3.org/2000/01/rdf-schema#label |
Keratin 14
|
gptkbp:involvedIn |
structural integrity of skin
|
gptkbp:locatedIn |
basal layer of epidermis
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_17q21.2
|
gptkbp:marking |
basal cells
|
gptkbp:molecularWeight |
50 kDa
|
gptkbp:mutationAssociatedWith |
gptkb:epidermolysis_bullosa_simplex
skin blistering disorders |
gptkbp:OMIM |
148066
|
gptkbp:structure |
alpha-helical protein
|
gptkbp:UniProtID |
P02533
|
gptkbp:bfsParent |
gptkb:K14
|
gptkbp:bfsLayer |
7
|