KRAS-mutant colorectal cancer
GPTKB entity
Statements (19)
Predicate | Object |
---|---|
gptkbp:instanceOf |
colorectal cancer subtype
|
gptkbp:associatedWith |
precision medicine
metastatic colorectal cancer tumor progression poor prognosis RAS pathway activation reduced response to cetuximab reduced response to panitumumab |
gptkbp:detects |
molecular testing
|
gptkbp:has_genetic_alteration |
gptkb:KRAS_mutation
|
gptkbp:has_primary_site |
colon
rectum |
https://www.w3.org/2000/01/rdf-schema#label |
KRAS-mutant colorectal cancer
|
gptkbp:is_resistant_to |
anti-EGFR therapy
|
gptkbp:is_treated_with |
chemotherapy
targeted therapy |
gptkbp:studiedBy |
oncology research
|
gptkbp:bfsParent |
gptkb:EGFR_inhibitors_(in_colorectal_cancer)
|
gptkbp:bfsLayer |
7
|