Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Epilepsy
|
| gptkbp:abbreviation |
gptkb:JME
|
| gptkbp:affects |
central nervous system
|
| gptkbp:alsoKnownAs |
Janz syndrome
|
| gptkbp:associatedWith |
photosensitivity
|
| gptkbp:contraindicatedDrugs |
gptkb:phenytoin
gptkb:carbamazepine |
| gptkbp:diagnosedBy |
gptkb:EEG
clinical history |
| gptkbp:EEGFinding |
generalized 4-6 Hz polyspike and wave discharges
|
| gptkbp:field |
neurology
|
| gptkbp:firstDescribed |
Hermann Janz
|
| gptkbp:frequency |
daily myoclonic jerks
|
| gptkbp:gender |
slightly more common in females
|
| gptkbp:geneticStudies |
yes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Juvenile Myoclonic Epilepsy
|
| gptkbp:ICD-10_code |
G40.3
|
| gptkbp:inheritance |
complex genetic
|
| gptkbp:longTermManagement |
lifelong medication often required
|
| gptkbp:MeSH_ID |
D020274
|
| gptkbp:MRI |
usually normal
|
| gptkbp:notable_for |
GABRA1
CACNB4 CLCN2 EFHC1 |
| gptkbp:OMIM |
254770
|
| gptkbp:onset |
childhood
adolescence |
| gptkbp:parentDisorder |
Idiopathic generalized epilepsy
|
| gptkbp:prevalence |
5-10% of all epilepsies
most common generalized epilepsy syndrome |
| gptkbp:prognosis |
good seizure control with medication
lifelong tendency to seizures |
| gptkbp:remissionRate |
low without medication
|
| gptkbp:riskFactor |
family history of epilepsy
|
| gptkbp:seizureTiming |
often after awakening
|
| gptkbp:seizureType |
absence
generalized myoclonic tonic-clonic |
| gptkbp:symptom |
absence seizures
generalized tonic-clonic seizures myoclonic jerks |
| gptkbp:treatment |
gptkb:valproic_acid
gptkb:lamotrigine gptkb:levetiracetam |
| gptkbp:triggeredBy |
gptkb:beer
stress sleep deprivation |
| gptkbp:typicalOnsetAge |
12-18 years
|
| gptkbp:bfsParent |
gptkb:D004239
|
| gptkbp:bfsLayer |
8
|