Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:approvedBy |
gptkb:European_Medicines_Agency
gptkb:U.S._Food_and_Drug_Administration 2005 |
| gptkbp:ATCCode |
C01EB17
|
| gptkbp:bioavailability |
40%
|
| gptkbp:brand |
gptkb:Procoralan
Corlanor |
| gptkbp:CASNumber |
155274-86-5
|
| gptkbp:contraindication |
gptkb:sick_sinus_syndrome
severe hypotension acute decompensated heart failure pacemaker dependence |
| gptkbp:discoveredBy |
gptkb:Servier_Laboratories
|
| gptkbp:eliminationHalfLife |
6 hours
|
| gptkbp:hasMolecularFormula |
C27H36N2O5
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ivabradine
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits funny current (If) in sinoatrial node
|
| gptkbp:metabolism |
gptkb:CYP3A4
liver |
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
hypertension
bradycardia phosphenes |
| gptkbp:usedFor |
heart failure
angina |
| gptkbp:bfsParent |
gptkb:Servier
gptkb:Servier_Pharmaceuticals |
| gptkbp:bfsLayer |
7
|