Ig G4-related kidney disease
GPTKB entity
Statements (67)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:healthcare_organization
|
gptkbp:bfsLayer |
3
|
gptkbp:bfsParent |
gptkb:healthcare_organization
|
gptkbp:affects |
kidneys
|
gptkbp:associated_with |
Ig G4 antibodies
|
gptkbp:can_be_extended_by |
other kidney diseases
|
gptkbp:can_lead_to |
kidney damage
kidney failure |
gptkbp:caused_by |
chronic kidney disease
|
gptkbp:exhibits |
weight loss
|
gptkbp:first_described_by |
gptkb:2003
|
gptkbp:has_achievements |
gptkb:healthcare_organization
|
https://www.w3.org/2000/01/rdf-schema#label |
Ig G4-related kidney disease
|
gptkbp:involves |
plasma cells
|
gptkbp:is_associated_with |
thrombocytopenia
pancreatitis lymphadenopathy autoimmune conditions elevated serum Ig E levels biliary involvement hypocomplementemia |
gptkbp:is_characterized_by |
inflammation
fibrosis plasma cell infiltration Ig G4-positive plasma cells high serum Ig G4 levels |
gptkbp:is_considered |
a rare disease
a chronic condition a rare cause of kidney disease a systemic disease an underdiagnosed condition |
gptkbp:is_evaluated_by |
clinical criteria
|
gptkbp:is_linked_to |
chronic pain
chronic inflammation vascular complications autoimmune pancreatitis increased risk of malignancy |
gptkbp:is_noted_for |
its relapsing nature
|
gptkbp:is_often_used_in |
males
|
gptkbp:is_part_of |
Ig G4-related disease spectrum
systemic Ig G4-related disease |
gptkbp:is_recognized_by |
imaging studies
histological examination |
gptkbp:is_used_for |
fatigue
abdominal pain fever joint pain neurological symptoms skin lesions edema proteinuria hematuria |
gptkbp:managed_by |
patient education
multidisciplinary teams supportive care lifestyle changes |
gptkbp:occurs_in |
adults
other Ig G4-related diseases |
gptkbp:recognizes |
blood tests
|
gptkbp:requires |
surgical intervention
immunosuppressive therapy long-term follow-up |
gptkbp:social_responsibility |
biopsy
|
gptkbp:treatment |
gptkb:mycophenolate_mofetil
gptkb:rituximab gptkb:azathioprine corticosteroids |