|
gptkbp:instanceOf
|
gptkb:Anticholinergic_drug
gptkb:Muscarinic_antagonist
gptkb:Tropane_alkaloid
|
|
gptkbp:ATCCode
|
A03BA03
|
|
gptkbp:CASNumber
|
80-16-0
|
|
gptkbp:chemicalFormula
|
C17H23NO3
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
gptkb:glaucoma
obstructive uropathy
obstructive gastrointestinal disease
|
|
gptkbp:discoveredBy
|
Friedrich Jobst
|
|
gptkbp:discoveredIn
|
1833
|
|
gptkbp:eliminationHalfLife
|
2–3.5 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
gptkb:Datura_stramonium
gptkb:Mandragora_officinarum
gptkb:Atropa_belladonna
gptkb:Hyoscyamus_niger
|
|
gptkbp:hasEnantiomer
|
gptkb:Scopolamine
|
|
gptkbp:isomerOf
|
gptkb:Atropine
|
|
gptkbp:IUPACName
|
(S)-2-[(1R,3r,5S)-3-hydroxy-2-phenyl-1-azabicyclo[3.2.1]oct-8-yl] acetate
|
|
gptkbp:KEGGID
|
D08013
|
|
gptkbp:legalStatus
|
prescription only (US)
|
|
gptkbp:mechanismOfAction
|
blocks muscarinic acetylcholine receptors
|
|
gptkbp:meltingPoint
|
108–110 °C
|
|
gptkbp:MeSH_ID
|
D006929
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
289.37 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
CHEMBL1201207
DB00422
154417
CHEBI:16647
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
subcutaneous
intravenous
sublingual
|
|
gptkbp:sideEffect
|
confusion
constipation
blurred vision
tachycardia
dry mouth
urinary retention
|
|
gptkbp:UNII
|
V628O1P09H
|
|
gptkbp:usedFor
|
treatment of irritable bowel syndrome
treatment of Parkinson's disease symptoms
treatment of gastrointestinal disorders
treatment of peptic ulcers
|
|
gptkbp:bfsParent
|
gptkb:Burundanga
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Hyoscyamine
|