Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Tropane alkaloid
Anticholinergic drug Muscarinic antagonist |
| gptkbp:ATCCode |
A03BA03
|
| gptkbp:CASNumber |
80-16-0
|
| gptkbp:chemicalFormula |
C17H23NO3
|
| gptkbp:contraindication |
gptkb:myasthenia_gravis
glaucoma obstructive uropathy obstructive gastrointestinal disease |
| gptkbp:discoveredBy |
Friedrich Jobst
|
| gptkbp:discoveredIn |
1833
|
| gptkbp:eliminationHalfLife |
2–3.5 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:foundIn |
gptkb:Datura_stramonium
gptkb:Mandragora_officinarum gptkb:Atropa_belladonna gptkb:Hyoscyamus_niger |
| gptkbp:hasEnantiomer |
gptkb:Scopolamine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hyoscyamine
|
| gptkbp:isomerOf |
gptkb:Atropine
|
| gptkbp:IUPACName |
(S)-2-[(1R,3r,5S)-3-hydroxy-2-phenyl-1-azabicyclo[3.2.1]oct-8-yl] acetate
|
| gptkbp:KEGGID |
D08013
|
| gptkbp:legalStatus |
prescription only (US)
|
| gptkbp:mechanismOfAction |
blocks muscarinic acetylcholine receptors
|
| gptkbp:meltingPoint |
108–110 °C
|
| gptkbp:MeSH_ID |
D006929
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
289.37 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
CHEMBL1201207
DB00422 154417 CHEBI:16647 |
| gptkbp:routeOfAdministration |
oral
intramuscular subcutaneous intravenous sublingual |
| gptkbp:sideEffect |
confusion
constipation blurred vision tachycardia dry mouth urinary retention |
| gptkbp:UNII |
V628O1P09H
|
| gptkbp:usedFor |
treatment of irritable bowel syndrome
treatment of Parkinson's disease symptoms treatment of gastrointestinal disorders treatment of peptic ulcers |
| gptkbp:bfsParent |
gptkb:Burundanga
|
| gptkbp:bfsLayer |
6
|