|
gptkbp:instance_of
|
gptkb:Fullmetal_Alchemist
gptkb:antagonist
|
|
gptkbp:antidote_for
|
cholinergic toxicity
|
|
gptkbp:bioavailability
|
100% when administered intravenously
|
|
gptkbp:casnumber
|
51-55-8
|
|
gptkbp:chemical_formula
|
C17 H23 NO3
|
|
gptkbp:clinical_use
|
cardiology
pediatric medicine
emergency medicine
ophthalmology
|
|
gptkbp:contraindication
|
gptkb:Ophthalmology
gptkb:myasthenia_gravis
urinary retention
prostatic hypertrophy
tachyarrhythmias
|
|
gptkbp:discovered_by
|
gptkb:Atropa_belladonna
|
|
gptkbp:displacement
|
from muscarinic receptors
|
|
gptkbp:dissolved
|
soluble in alcohol
slightly soluble in water
soluble in chloroform
|
|
gptkbp:effect_on_cns
|
can cause sedation
|
|
gptkbp:effect_on_heart_rate
|
increases heart rate
|
|
gptkbp:effect_on_pupil
|
dilates pupils
|
|
gptkbp:effect_on_secretions
|
decreases secretions
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Atropine
|
|
gptkbp:lifespan
|
2 hours
|
|
gptkbp:mass
|
289.37 g/mol
|
|
gptkbp:mechanism_of_action
|
blocks acetylcholine receptors
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:p_hlevel
|
9.7
|
|
gptkbp:produced_by
|
tropacocaine
tropine
|
|
gptkbp:related_products
|
gptkb:scopolamine
hyoscyamine
|
|
gptkbp:replaces
|
1833
|
|
gptkbp:rounds
|
renal
|
|
gptkbp:route_of_administration
|
intravenous
subcutaneous
intramuscular
|
|
gptkbp:side_effect
|
constipation
dry mouth
blurred vision
tachycardia
urinary retention
|
|
gptkbp:trade
|
gptkb:Atro_Pen
gptkb:Atropine_sulfate
gptkb:Isopto_Atropine
|
|
gptkbp:used_for
|
organophosphate poisoning
bradycardia
anesthesia adjunct
|
|
gptkbp:bfsParent
|
gptkb:Bella_Donna
|
|
gptkbp:bfsLayer
|
5
|