Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
alkaloid antimuscarinic agent |
| gptkbp:antidote |
nerve agent poisoning
organophosphate poisoning |
| gptkbp:ATCCode |
A03BA01
|
| gptkbp:CASNumber |
51-55-8
|
| gptkbp:category |
alkaloid
antidote antispasmodic anticholinergic mydriatic |
| gptkbp:chemicalFormula |
C17H23NO3
|
| gptkbp:contraindication |
gptkb:myasthenia_gravis
glaucoma prostatic hypertrophy |
| gptkbp:discoveredBy |
gptkb:Friedrich_Sertürner
|
| gptkbp:discoveredIn |
1831
|
| gptkbp:eliminationHalfLife |
2-4 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:foundIn |
gptkb:Datura_stramonium
gptkb:Atropa_belladonna gptkb:Hyoscyamus_niger |
| https://www.w3.org/2000/01/rdf-schema#label |
Atropine
|
| gptkbp:IUPACName |
(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
muscarinic acetylcholine receptor antagonist
|
| gptkbp:meltingPoint |
115 °C
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
289.37 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
174
DB00572 |
| gptkbp:routeOfAdministration |
intramuscular
subcutaneous intravenous ophthalmic |
| gptkbp:sideEffect |
confusion
constipation blurred vision tachycardia dry mouth urinary retention |
| gptkbp:UNII |
7C0697DR9I
|
| gptkbp:usedFor |
antidote for organophosphate poisoning
dilate pupils (mydriasis) preanesthetic to reduce salivation treatment of bradycardia |
| gptkbp:bfsParent |
gptkb:Antidotes
gptkb:Antidote |
| gptkbp:bfsLayer |
5
|