|
gptkbp:instanceOf
|
gptkb:drug
gptkb:antimuscarinic_agent
gptkb:alkaloid
|
|
gptkbp:antidote
|
nerve agent poisoning
organophosphate poisoning
|
|
gptkbp:ATCCode
|
A03BA01
|
|
gptkbp:CASNumber
|
51-55-8
|
|
gptkbp:category
|
gptkb:alkaloid
gptkb:antidote
antispasmodic
anticholinergic
mydriatic
|
|
gptkbp:chemicalFormula
|
C17H23NO3
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
gptkb:glaucoma
prostatic hypertrophy
|
|
gptkbp:discoveredBy
|
gptkb:Friedrich_Sertürner
|
|
gptkbp:discoveredIn
|
1831
|
|
gptkbp:eliminationHalfLife
|
2-4 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
gptkb:Datura_stramonium
gptkb:Atropa_belladonna
gptkb:Hyoscyamus_niger
|
|
gptkbp:IUPACName
|
(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
muscarinic acetylcholine receptor antagonist
|
|
gptkbp:meltingPoint
|
115 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
289.37 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
174
DB00572
|
|
gptkbp:routeOfAdministration
|
intramuscular
subcutaneous
intravenous
ophthalmic
|
|
gptkbp:sideEffect
|
confusion
constipation
blurred vision
tachycardia
dry mouth
urinary retention
|
|
gptkbp:UNII
|
7C0697DR9I
|
|
gptkbp:usedFor
|
antidote for organophosphate poisoning
dilate pupils (mydriasis)
preanesthetic to reduce salivation
treatment of bradycardia
|
|
gptkbp:bfsParent
|
gptkb:Antidote
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Atropine
|