Hydroxyethylated starch

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf colloid solution
plasma volume expander
gptkbp:administeredBy intravenous infusion
gptkbp:alternativeTo albumin
gelatin solutions
gptkbp:amendedBy hydroxyethylation
gptkbp:ATCCode gptkb:B05AA07
gptkbp:brand Hespan
Hetastarch
Pentastarch
Tetrastarch
Voluven
gptkbp:CASNumber gptkb:9005-27-0
gptkbp:contraindication sepsis
renal impairment
critical illness
gptkbp:derivedFrom starch
gptkbp:eliminatedIn renal
gptkbp:halfLife varies (hours to days depending on type)
gptkbp:hasRegulatoryStatus restricted in EU
boxed warning in US
https://www.w3.org/2000/01/rdf-schema#label Hydroxyethylated starch
gptkbp:molecularWeight varies (commonly 130-450 kDa)
gptkbp:regulates gptkb:FDA
gptkb:EMA
gptkbp:riskFactor bleeding
anaphylactoid reactions
kidney injury
tissue storage
gptkbp:sideEffect pruritus
renal dysfunction
coagulopathy
gptkbp:usedFor treatment of hypovolemia
gptkbp:bfsParent gptkb:Hydroxyethyl_starch
gptkbp:bfsLayer 7