Hodgkin disease

GPTKB entity

Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
gptkbp:affects lymphatic system
gptkbp:age older adults
young adults
gptkbp:alsoKnownAs Hodgkin lymphoma
gptkbp:characterizedBy gptkb:Reed-Sternberg_cells
gptkbp:complication cardiac toxicity (from treatment)
infertility (from treatment)
secondary malignancies
gptkbp:diagnosedBy imaging studies
lymph node biopsy
gptkbp:differentialDiagnosis gptkb:infectious_mononucleosis
leukemia
gptkbp:firstDescribed 1832
gptkbp:gender slightly more common in males
gptkbp:hasOrphanetID ORPHA:776
https://www.w3.org/2000/01/rdf-schema#label Hodgkin disease
gptkbp:ICD-10_code gptkb:C81
gptkbp:incidence about 3 per 100,000 per year (US)
gptkbp:marking CD15 positive
CD30 positive
gptkbp:MeSH_ID D006689
gptkbp:mortalityRate low with modern therapy
gptkbp:namedAfter gptkb:Thomas_Hodgkin
gptkbp:OMIM 236000
gptkbp:prevalence rare
gptkbp:prognosis generally favorable with treatment
gptkbp:riskFactor gptkb:Epstein-Barr_virus_infection
family history
immunosuppression
gptkbp:stagingSystem gptkb:Ann_Arbor_staging
gptkbp:subspecies gptkb:nodular_sclerosis
lymphocyte-depleted
lymphocyte-rich
mixed cellularity
gptkbp:symptom fever
weight loss
night sweats
painless lymphadenopathy
gptkbp:treatment radiation therapy
chemotherapy
immunotherapy
gptkbp:bfsParent gptkb:Hodgkin's_lymphoma
gptkbp:bfsLayer 6