Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:affects |
animals
humans lungs central nervous system liver spleen adrenal glands |
| gptkbp:canBeAsymptomatic |
true
|
| gptkbp:canBeSevereIn |
immunocompromised individuals
|
| gptkbp:category |
gptkb:Fungi
zoonosis respiratory disease |
| gptkbp:cause |
pulmonary infection
disseminated infection |
| gptkbp:causedBy |
gptkb:Histoplasma_capsulatum
|
| gptkbp:complication |
chronic pulmonary histoplasmosis
fibrosing mediastinitis mediastinal granuloma |
| gptkbp:diagnosedBy |
gptkb:culture
serology antigen test |
| gptkbp:endemicTo |
gptkb:Ohio_River_Valley
Mississippi River Valley |
| gptkbp:firstDescribed |
gptkb:Samuel_Taylor_Darling
1906 |
| https://www.w3.org/2000/01/rdf-schema#label |
Histoplasmosis
|
| gptkbp:ICD-10_code |
B39
|
| gptkbp:MeSH_ID |
D006882
|
| gptkbp:mortalityRate |
high in untreated disseminated cases
low in healthy individuals |
| gptkbp:prevention |
use of protective equipment
avoid exposure to contaminated soil |
| gptkbp:riskFactor |
cave exploration
demolition work exposure to bat droppings exposure to bird droppings |
| gptkbp:symptom |
fever
fatigue cough chest pain body aches |
| gptkbp:transmission |
inhalation of fungal spores
|
| gptkbp:transmittedBy |
person-to-person contact
|
| gptkbp:treatment |
gptkb:amphotericin_B
itraconazole |
| gptkbp:bfsParent |
gptkb:disease
|
| gptkbp:bfsLayer |
4
|