Hi-C data

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf genomics data type
gptkbp:analyzes bioinformatics tools
chromatin interactions
gptkbp:depot gptkb:ENCODE
gptkb:4D_Nucleome_Data_Portal
gptkb:GEO
gptkbp:enables identification of chromatin loops
identification of compartments
identification of topologically associating domains
gptkbp:firstDescribed gptkb:Lieberman-Aiden_et_al.
gptkbp:firstPublished 2009
gptkbp:format .cool
.hic
.mcool
https://www.w3.org/2000/01/rdf-schema#label Hi-C data
gptkbp:processor gptkb:HiC-Pro
gptkb:HiCExplorer
HOMER
Juicer
gptkbp:producedBy gptkb:Hi-C_experiment
gptkbp:relatedTo gptkb:ChIA-PET_data
ATAC-seq data
Capture-C data
gptkbp:requires sequencing
PCR amplification
crosslinking
high-throughput sequencing
ligation
restriction enzyme digestion
gptkbp:resolution genome size
restriction enzyme choice
sequencing depth
varies from kilobase to megabase
gptkbp:species gptkb:Drosophila
gptkb:human
gptkb:mouse
gptkb:yeast
gptkbp:type contact matrix
interaction frequency
gptkbp:usedFor developmental biology
cancer genomics
comparative genomics
3D genome organization analysis
identifying structural variants
studying genome folding
gptkbp:usedIn gptkb:chromosome_conformation_capture
gptkbp:visualizes gptkb:HiGlass
gptkb:Juicebox
gptkbp:bfsParent gptkb:ENCODE_Project
gptkbp:bfsLayer 5