Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cancer
gptkb:liver_disease |
| gptkbp:affectsOrgan |
Liver
|
| gptkbp:alsoKnownAs |
gptkb:HCC
|
| gptkbp:canMetastasizeTo |
gptkb:bone
Lung Lymph nodes |
| gptkbp:commonAgeGroup |
Middle-aged and older adults
|
| gptkbp:complication |
Liver failure
Ascites Portal hypertension Variceal bleeding |
| gptkbp:diagnosedBy |
Liver biopsy
Imaging (CT, MRI, ultrasound) Alpha-fetoprotein blood test |
| gptkbp:firstDescribed |
19th century
|
| gptkbp:histology |
Malignant hepatocytes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hepatocellular Carcinoma
|
| gptkbp:ICD-10_code |
C22.0
|
| gptkbp:incidence |
More common in men
Higher prevalence in Asia and Africa Most common primary liver cancer |
| gptkbp:marking |
Alpha-fetoprotein (AFP)
|
| gptkbp:mortalityRate |
High
|
| gptkbp:prevention |
gptkb:Hepatitis_B_vaccination
Avoiding aflatoxin exposure Managing hepatitis infections Reducing alcohol consumption |
| gptkbp:prognosis |
Better if detected early
Poor if advanced |
| gptkbp:riskFactor |
gptkb:Alcohol_abuse
Cirrhosis Aflatoxin exposure Chronic hepatitis B infection Chronic hepatitis C infection Nonalcoholic fatty liver disease |
| gptkbp:stagingSystem |
gptkb:TNM_classification
Barcelona Clinic Liver Cancer (BCLC) |
| gptkbp:subspecies |
Primary liver cancer
|
| gptkbp:symptom |
Weight loss
Fatigue Jaundice Abdominal pain |
| gptkbp:treatment |
radiation therapy
immunotherapy Targeted therapy Surgical resection Liver transplantation Ablation therapy Transarterial chemoembolization (TACE) |
| gptkbp:bfsParent |
gptkb:D008582
|
| gptkbp:bfsLayer |
6
|