|
gptkbp:instanceOf
|
gptkb:clinical_trial
|
|
gptkbp:ageRange
|
40-80 years
|
|
gptkbp:conductedBy
|
gptkb:University_of_Oxford
gptkb:Medical_Research_Council_(MRC)
gptkb:British_Heart_Foundation_(BHF)
|
|
gptkbp:country
|
gptkb:United_Kingdom
|
|
gptkbp:endDate
|
2001
|
|
gptkbp:focus
|
cardiovascular disease prevention
cholesterol lowering
|
|
gptkbp:fullName
|
gptkb:MRC/BHF_Heart_Protection_Study
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Heart Protection Study
|
|
gptkbp:includes
|
high risk of cardiovascular disease
|
|
gptkbp:intervention
|
gptkb:simvastatin
antioxidant vitamins
|
|
gptkbp:participants
|
20536
|
|
gptkbp:principalInvestigator
|
gptkb:Rory_Collins
gptkb:Jane_Armitage
|
|
gptkbp:publicationYear
|
2002
|
|
gptkbp:publishedIn
|
gptkb:The_Lancet
|
|
gptkbp:recognizedBy
|
gptkb:ISRCTN48489393
|
|
gptkbp:result
|
antioxidant vitamins had no significant effect
reduction in all-cause mortality
reduction in cardiovascular events
simvastatin reduced major vascular events
|
|
gptkbp:startYear
|
1994
|
|
gptkbp:trial
|
gptkb:clinical_trial
double-blind
placebo-controlled
|
|
gptkbp:website
|
https://www.ctsu.ox.ac.uk/research/mega-trials/hps
|
|
gptkbp:bfsParent
|
gptkb:Rory_Collins
|
|
gptkbp:bfsLayer
|
6
|