|
gptkbp:instanceOf
|
benzodiazepine
|
|
gptkbp:ATCCode
|
N05BA11
|
|
gptkbp:brand
|
Paxipam
|
|
gptkbp:CASNumber
|
23092-17-3
|
|
gptkbp:category
|
GABA-A receptor positive allosteric modulator
chloroarene
lactam
fluoroarene
|
|
gptkbp:chemicalFormula
|
C17H12ClFN2O
|
|
gptkbp:developedBy
|
gptkb:Schering-Plough
|
|
gptkbp:discontinued
|
yes
|
|
gptkbp:eliminationHalfLife
|
14-24 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Halazepam
|
|
gptkbp:introducedIn
|
1970s
|
|
gptkbp:IUPACName
|
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
|
|
gptkbp:legalStatus
|
gptkb:Schedule_IV
|
|
gptkbp:mechanismOfAction
|
GABA-A receptor positive allosteric modulator
|
|
gptkbp:meltingPoint
|
178-180°C
|
|
gptkbp:metabolism
|
nordazepam
|
|
gptkbp:molecularWeight
|
314.75 g/mol
|
|
gptkbp:pregnancyCategory
|
D
|
|
gptkbp:proteinBinding
|
87%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201202
3567
3445
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
dizziness
fatigue
drowsiness
impaired coordination
|
|
gptkbp:synonym
|
Paxipam
|
|
gptkbp:UNII
|
0W6E4725ZE
|
|
gptkbp:usedFor
|
treatment of anxiety
|
|
gptkbp:withdrawn
|
yes
|
|
gptkbp:bfsParent
|
gptkb:N05BA
|
|
gptkbp:bfsLayer
|
7
|