Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
gptkb:Horner–Wadsworth–Emmons_reaction
|
| gptkbp:application |
stereoselective synthesis of alkenes
|
| gptkbp:basisFor |
strong base (e.g., sodium hydride, potassium tert-butoxide)
|
| gptkbp:category |
carbon–carbon bond forming reaction
|
| gptkbp:criteria |
E-selectivity (trans-alkenes)
|
| gptkbp:firstReported |
1958
|
| https://www.w3.org/2000/01/rdf-schema#label |
HWE reaction
|
| gptkbp:mechanismOfAction |
nucleophilic addition-elimination
|
| gptkbp:namedAfter |
gptkb:Leopold_Horner
gptkb:William_D._Emmons gptkb:William_S._Wadsworth |
| gptkbp:product |
alkene
|
| gptkbp:reactant |
aldehyde
ketone phosphonate-stabilized carbanion |
| gptkbp:relatedTo |
gptkb:Wittig_reaction
|
| gptkbp:solvent |
polar aprotic solvents
|
| gptkbp:type |
olefination
|
| gptkbp:usedIn |
organic synthesis
|
| gptkbp:bfsParent |
gptkb:Horner–Wadsworth–Emmons_reaction
|
| gptkbp:bfsLayer |
6
|