Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
3-hydroxy-3-methylglutaryl-CoA lyase
HMGCL |
| gptkbp:catalyzes |
cleavage of HMG-CoA to acetyl-CoA and acetoacetate
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:deficiencyCauses |
HMG-CoA lyase deficiency
|
| gptkbp:EC_number |
4.1.3.4
|
| gptkbp:encodedBy |
HMGCL gene
|
| gptkbp:foundIn |
mitochondria
peroxisomes |
| https://www.w3.org/2000/01/rdf-schema#label |
HMG-CoA lyase
|
| gptkbp:involves |
ketogenesis
leucine catabolism |
| gptkbp:product |
acetyl-CoA
acetoacetate |
| gptkbp:substrate |
3-hydroxy-3-methylglutaryl-CoA
|
| gptkbp:bfsParent |
gptkb:HMG-CoA
|
| gptkbp:bfsLayer |
8
|