HCV genome

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:affiliatedWith gptkb:Hepatitis_C_virus
gptkbp:contains 3' untranslated region (3' UTR)
5' untranslated region (5' UTR)
internal ribosome entry site (IRES)
gptkbp:discoveredIn 1989
gptkbp:encodes structural proteins
NS3 protein
NS5A protein
NS5B protein
core protein
NS2 protein
NS4A protein
NS4B protein
envelope glycoprotein E1
envelope glycoprotein E2
nonstructural proteins
p7 protein
gptkbp:function template for viral protein synthesis
template for viral replication
gptkbp:genomeType single-stranded RNA
gptkbp:genotypes at least 7 major genotypes
https://www.w3.org/2000/01/rdf-schema#label HCV genome
gptkbp:length approximately 9600 nucleotides
gptkbp:polyprotein cleaved by viral and host proteases
translated as a single polyprotein
gptkbp:replicatesIn gptkb:cytoplasm
gptkbp:sensitivity positive-sense
gptkbp:subspecies multiple subtypes per genotype
gptkbp:variant high genetic variability
gptkbp:bfsParent gptkb:hepatitis_C_virus_envelope_protein_E2
gptkbp:bfsLayer 8