Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activeSiteResidue |
GDD motif
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:encodedBy |
HCV NS5B gene
|
| gptkbp:foundIn |
gptkb:Hepatitis_C_virus
|
| gptkbp:function |
RNA-dependent RNA polymerase
|
| https://www.w3.org/2000/01/rdf-schema#label |
HCV NS5B polymerase
|
| gptkbp:inhibitedBy |
nucleoside analogs
non-nucleoside inhibitors |
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
~65 kDa
|
| gptkbp:PDB |
2XI3
|
| gptkbp:requires |
HCV replication
|
| gptkbp:role |
HCV genome replication
|
| gptkbp:structureType |
right-hand fold
|
| gptkbp:target |
gptkb:Sofosbuvir
antiviral drugs Beclabuvir Dasabuvir |
| gptkbp:UniProtID |
P26663
|
| gptkbp:bfsParent |
gptkb:Sofosbuvir
|
| gptkbp:bfsLayer |
6
|