Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:virus
|
| gptkbp:encodedBy |
NS5A gene
|
| gptkbp:foundIn |
gptkb:Hepatitis_C_virus
|
| gptkbp:function |
viral replication
modulation of host cell pathways |
| https://www.w3.org/2000/01/rdf-schema#label |
HCV NS5A protein
|
| gptkbp:interactsWith |
host cell proteins
HCV NS5B protein HCV core protein |
| gptkbp:involvedIn |
immune evasion
lipid metabolism modulation |
| gptkbp:locale |
endoplasmic reticulum membrane
|
| gptkbp:molecularWeight |
~56 kDa
|
| gptkbp:phosphorylates |
yes
|
| gptkbp:role |
virus assembly
HCV RNA replication complex |
| gptkbp:structure |
three domains (I, II, III)
|
| gptkbp:target |
gptkb:elbasvir
gptkb:daclatasvir direct-acting antivirals ledipasvir velpatasvir ombitasvir |
| gptkbp:bfsParent |
gptkb:Zepatier
|
| gptkbp:bfsLayer |
6
|