Statements (53)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:vaccine
|
gptkbp:bfsLayer |
5
|
gptkbp:bfsParent |
gptkb:HBV
|
gptkbp:advocates_for |
required before administration
|
gptkbp:associated_with |
reduction in liver cancer rates
|
gptkbp:can_be_used_with |
gptkb:MMR_vaccine
Hib vaccine DTP vaccine |
gptkbp:clinical_trial |
demonstrated safety and efficacy
|
gptkbp:community_impact |
reduced incidence of Hepatitis B
|
gptkbp:contraindication |
severe allergic reaction to a component
|
gptkbp:covered_by |
increasing
|
gptkbp:developed_by |
Recombinant DNA technology
|
gptkbp:dosage_form |
not routinely recommended
at birth 1-2 months after first dose 6-18 months after first dose |
gptkbp:duration |
at least 20 years
|
gptkbp:first_introduced |
gptkb:1981
|
gptkbp:healthcare |
to eliminate Hepatitis B
|
https://www.w3.org/2000/01/rdf-schema#label |
HBV vaccine
|
gptkbp:is_available_in |
monovalent and combination vaccines
|
gptkbp:is_effective_against |
over 90% in healthy individuals
|
gptkbp:is_protected_by |
Hepatitis B infection
|
gptkbp:is_vulnerable_to |
varies by region
requires refrigeration increased in recent years continues to evolve. subunit vaccine ongoing research for improved formulations high in adults updated periodically by health organizations high in children high in adolescents high in infants improving in low-income countries managed by health authorities |
gptkbp:manager |
intramuscular injection
|
gptkbp:marketed_as |
various brand names
|
gptkbp:part_of |
routine childhood immunization schedule
|
gptkbp:performance |
3 doses
|
gptkbp:recommendation |
included in the EPI (Expanded Program on Immunization)
|
gptkbp:side_effect |
fatigue
fever rarely severe mild pain at injection site |
gptkbp:storage |
2-8 degrees Celsius
|
gptkbp:suitable_for |
newborns
healthcare workers CDC (Centers for Disease Control and Prevention) ACIP (Advisory Committee on Immunization Practices) |
gptkbp:targets |
gptkb:Hepatitis_B_virus
|
gptkbp:type |
gptkb:recombinant_vaccine
|