H5N1 influenza virus

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf influenza
gptkbp:animalReservoir domestic poultry
wild waterfowl
gptkbp:antiviralTreatment gptkb:oseltamivir
gptkb:zanamivir
gptkbp:biosafetyLevel gptkb:BSL-3
gptkbp:cause gptkb:highly_pathogenic_avian_influenza_(HPAI)
gptkb:avian_influenza
gptkb:human_influenza
gptkbp:discoveredBy gptkb:China
1996
Chinese scientists
gptkbp:family gptkb:Orthomyxoviridae
gptkbp:genomeType single-stranded RNA
gptkbp:genus gptkb:Alphainfluenzavirus
gptkbp:hemagglutininType H5
gptkbp:hostedBy birds
humans
mammals
https://www.w3.org/2000/01/rdf-schema#label H5N1 influenza virus
gptkbp:mortalityRateInHumans high
gptkbp:mutationAssociatedWith HA Q222L
PB2 E627K
gptkbp:neuraminidaseType gptkb:N1
gptkbp:notableCaseFatalityRate ~60% (in reported human cases)
gptkbp:notableOutbreaks gptkb:2003–2004_Asia_outbreak
gptkb:2022–2023_global_outbreak
2006 Egypt outbreak
gptkbp:pandemicRisk yes
gptkbp:relatedTo gptkb:H1N1_influenza_virus
H7N9 influenza virus
gptkbp:spreadTo gptkb:Africa
gptkb:Europe
gptkb:North_America
gptkbp:studiedBy gptkb:Centers_for_Disease_Control_and_Prevention
gptkb:World_Health_Organization
gptkb:Food_and_Agriculture_Organization
gptkb:OIE_(World_Organisation_for_Animal_Health)
gptkbp:subspecies gptkb:Influenza_A_virus
gptkbp:symptom gptkb:pneumonia
fever
cough
sore throat
gptkbp:transmission contaminated environments
direct contact with infected birds
limited human-to-human transmission
gptkbp:vaccineAvailable yes (for poultry, limited for humans)
gptkbp:WHOConcernLevel pandemic potential
gptkbp:zoonotic yes
gptkbp:bfsParent gptkb:H1N1_influenza_virus
gptkbp:bfsLayer 6