Gonadotropin-Releasing Hormone
GPTKB entity
Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:item
|
| gptkbp:affects |
follicle-stimulating hormone levels
luteinizing hormone levels |
| gptkbp:antagonist |
gptkb:hypothalamus
anterior pituitary |
| gptkbp:enhances |
gptkb:anterior_pituitary_gland
|
| gptkbp:established |
testosterone
estrogen |
| gptkbp:has_role |
gptkb:menstrual_cycle
puberty |
| https://www.w3.org/2000/01/rdf-schema#label |
Gonadotropin-Releasing Hormone
|
| gptkbp:is_aimed_at |
gptkb:Gn_RH_agonists
Gn RH antagonists |
| gptkbp:is_analyzed_in |
hormonal therapies
cancer treatments endocrine disorders infertility treatments |
| gptkbp:is_associated_with |
polycystic ovary syndrome
hypogonadism delayed puberty fertility disorders hypothalamic amenorrhea |
| gptkbp:is_enhanced_by |
gptkb:kisspeptin
|
| gptkbp:is_essential_for |
fertility
|
| gptkbp:is_involved_in |
gptkb:oogenesis
gptkb:spermatogenesis mood regulation cell differentiation cell growth cell signaling circadian rhythms gene expression immune response metabolic processes neurotransmitter release cognitive function wound healing stress response immune function sleep regulation aging process tissue repair body weight regulation behavioral responses menopause gonadal function reproductive hormone regulation sexual differentiation androgen production estrogen production |
| gptkbp:is_known_for |
gptkb:Gn_RH
|
| gptkbp:is_studied_in |
neuroendocrinology
reproductive endocrinology |
| gptkbp:is_used_in |
hormone therapy
|
| gptkbp:lifespan |
approximately 2-4 minutes
|
| gptkbp:produced_by |
gptkb:hypothalamus
|
| gptkbp:regulates |
feedback mechanisms
gonadotropin secretion |
| gptkbp:stealth_features |
pulsatile manner
|
| gptkbp:bfsParent |
gptkb:GCRH
|
| gptkbp:bfsLayer |
5
|