Glucose-6-phosphate isomerase

URI: https://gptkb.org/entity/Glucose-6-phosphate_isomerase
GPTKB entity
Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:phosphoglucose_isomerase
autocrine motility factor
maturation factor
neuroleukin
phosphohexose isomerase
gptkbp:biologicalProcess carbohydrate metabolism
isomerase activity
gptkbp:catalyzes isomerization of glucose-6-phosphate to fructose-6-phosphate
gptkbp:cofactor none required
gptkbp:deficiencyCauses gptkb:nonspherocytic_hemolytic_anemia
gptkbp:discoveredBy 1950s
gptkbp:EC_number 5.3.1.9
gptkbp:expressedIn most tissues
gptkbp:foundIn gptkb:cytoplasm
gptkbp:gene gptkb:GPI
https://www.w3.org/2000/01/rdf-schema#label Glucose-6-phosphate isomerase
gptkbp:involves glycolysis
gluconeogenesis
gptkbp:locatedOnChromosome 19q13.11
gptkbp:molecularWeight ~63 kDa
gptkbp:OMIM 172400
gptkbp:PDB 1IRI
gptkbp:product fructose-6-phosphate
gptkbp:significance autoantigen in rheumatoid arthritis
gptkbp:structure homodimer
gptkbp:substrate gptkb:glucose-6-phosphate
gptkbp:UniProtID P06744
gptkbp:bfsParent gptkb:P42127
gptkbp:bfsLayer 7