Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
medication
|
| gptkbp:activeDuring |
metformin
|
| gptkbp:brand |
gptkb:Glucophage_XR
gptkb:Riomet Fortamet Glucophage |
| gptkbp:chemicalFormula |
C4H11N5O
|
| gptkbp:clinicalTrials |
first-line treatment
in combination with other agents metformin efficacy metformin safety |
| gptkbp:commonName |
500 mg
1000 mg |
| gptkbp:contraindication |
metabolic acidosis
renal impairment vitamin B12 deficiency lactic_acidosis |
| gptkbp:date |
2000
|
| gptkbp:dosageForm |
oral
|
| gptkbp:drugInterdiction |
true
|
| gptkbp:formulation |
extended-release tablet
|
| gptkbp:gestationPeriod |
B
|
| gptkbp:hasPopulation |
adults
children over 10 years |
| gptkbp:healthcare |
take with food
important for effectiveness do not crush or chew |
| https://www.w3.org/2000/01/rdf-schema#label |
Glucophage XR
|
| gptkbp:impact |
weight management
glycemic control |
| gptkbp:interactsWith |
alcohol
other diabetes medications |
| gptkbp:is_monitored_by |
kidney function
blood glucose levels |
| gptkbp:manufacturer |
gptkb:Bristol-Myers_Squibb
|
| gptkbp:marketedAs |
gptkb:Canada
gptkb:European_Union gptkb:United_States |
| gptkbp:offers |
varies by pharmacy
|
| gptkbp:operates_in |
A10BA02
|
| gptkbp:packaging |
blister pack
bottle |
| gptkbp:route |
oral
|
| gptkbp:sideEffect |
nausea
stomach upset diarrhea |
| gptkbp:storage |
room temperature
away from moisture |
| gptkbp:triggerType |
increases insulin sensitivity
decreases_hepatic_glucose_production |
| gptkbp:type |
true
|
| gptkbp:usedFor |
type 2 diabetes
|