Gilenya

GPTKB entity

Statements (41)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:approvalYear 2010
gptkbp:approvedBy gptkb:European_Union
gptkb:United_States
gptkbp:ATCCode gptkb:L04AA27
gptkbp:CASNumber gptkb:162359-55-9
gptkbp:chemicalFormula C19H33NO2
gptkbp:contraindication gptkb:second-_or_third-degree_AV_block
stroke
pregnancy
recent myocardial infarction
severe untreated sleep apnea
gptkbp:drugClass immunotherapy
gptkbp:drugInteraction immunosuppressants
live vaccines
antiarrhythmic drugs
gptkbp:eliminationHalfLife 6-9 days
gptkbp:genericName gptkb:fingolimod
https://www.w3.org/2000/01/rdf-schema#label Gilenya
gptkbp:indication relapsing forms of multiple sclerosis
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Novartis
gptkbp:marketedAs gptkb:Gilenya
gptkb:Fingolimod
gptkbp:mechanismOfAction sphingosine-1-phosphate receptor modulator
gptkbp:monitors eye examination
heart rate
blood pressure
liver function
gptkbp:patentExpired 2019 (US)
gptkbp:pregnancyCategory gptkb:X_(US)
gptkbp:pregnancyWarning may cause fetal harm
gptkbp:prescriptionStatus Rx-only
gptkbp:routeOfAdministration oral
gptkbp:sideEffect gptkb:macular_edema
bradycardia
increased risk of infections
liver enzyme elevation
gptkbp:usedFor multiple sclerosis
gptkbp:bfsParent gptkb:Novartis
gptkbp:bfsLayer 4