|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:administeredBy
|
topical application
intramuscular injection
intravenous injection
|
|
gptkbp:approvedBy
|
1960s
|
|
gptkbp:ATCCode
|
gptkb:J01GB03
|
|
gptkbp:bioavailability
|
not orally absorbed
|
|
gptkbp:CASNumber
|
1403-66-3
|
|
gptkbp:chemicalClass
|
gptkb:antibiotic
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
pregnancy (relative)
|
|
gptkbp:discoveredBy
|
Marvin Weinstein
|
|
gptkbp:discoveredIn
|
1963
|
|
gptkbp:eliminationHalfLife
|
2–3 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C21H43N5O7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Gentamicin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial protein synthesis
|
|
gptkbp:metabolism
|
not metabolized
|
|
gptkbp:notEffectiveAgainst
|
fungi
viruses
anaerobic bacteria
|
|
gptkbp:origin
|
natural product
|
|
gptkbp:pregnancyCategory
|
D
|
|
gptkbp:producedBy
|
gptkb:Micromonospora_purpurea
|
|
gptkbp:proteinBinding
|
0–30%
|
|
gptkbp:routeOfAdministration
|
IV
IM
topical
ophthalmic
|
|
gptkbp:sideEffect
|
nephrotoxicity
ototoxicity
neuromuscular blockade
|
|
gptkbp:synonym
|
Cidomycin
Garamycin
Gentacidin
|
|
gptkbp:treatment
|
gptkb:pneumonia
meningitis
skin infections
sepsis
endocarditis
urinary tract infections
eye infections
intra-abdominal infections
bone infections
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Streptomyces_species
gptkb:Micromonospora_species
|
|
gptkbp:bfsLayer
|
6
|