Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
GC-C
STa receptor guanylate cyclase C |
| gptkbp:associatedWith |
colorectal cancer
familial diarrhea syndrome |
| gptkbp:encodes |
guanylate cyclase 2C
|
| gptkbp:Entrez_Gene_ID |
2984
ENSG00000177133 |
| gptkbp:expressedIn |
intestinal epithelial cells
|
| gptkbp:function |
catalyzes conversion of GTP to cGMP
receptor for guanylin and uroguanylin |
| gptkbp:geneType |
protein-coding
|
| gptkbp:hasTranscriptVariant |
multiple
|
| gptkbp:HGNC_ID |
4686
|
| https://www.w3.org/2000/01/rdf-schema#label |
GUCY2C
|
| gptkbp:length |
1073 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12
|
| gptkbp:molecularWeight |
120 kDa
|
| gptkbp:mutationAssociatedWith |
can cause chronic diarrhea
can cause meconium ileus |
| gptkbp:OMIM |
601330
|
| gptkbp:orthologInMouse |
Gucy2c
|
| gptkbp:proteinFamily |
gptkb:guanylate_cyclase_family
|
| gptkbp:subcellularLocation |
apical membrane
|
| gptkbp:target |
bacterial heat-stable enterotoxin (STa)
|
| gptkbp:UniProtID |
P25092
|
| gptkbp:bfsParent |
gptkb:GUCY
|
| gptkbp:bfsLayer |
7
|