Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
antiviral drug
|
gptkbp:alsoKnownAs |
gptkb:sofosbuvir
|
gptkbp:approvedBy |
gptkb:FDA
2013 |
gptkbp:ATCCode |
gptkb:J05AX15
|
gptkbp:bioavailability |
high
|
gptkbp:CASNumber |
1190307-88-0
|
gptkbp:chemicalFormula |
C22H29FN3O9P
|
gptkbp:combinationTherapy |
ribavirin
ledipasvir velpatasvir |
gptkbp:developedBy |
gptkb:Gilead_Sciences
|
gptkbp:discoveredBy |
gptkb:Pharmasset
|
gptkbp:eliminationHalfLife |
0.4 hours (sofosbuvir), 27 hours (GS-331007 metabolite)
|
https://www.w3.org/2000/01/rdf-schema#label |
GS-7977
|
gptkbp:legalStatus |
prescription only
|
gptkbp:marketedAs |
gptkb:Sovaldi
|
gptkbp:mechanismOfAction |
gptkb:NS5B_polymerase_inhibitor
|
gptkbp:metabolism |
gptkb:GS-331007
|
gptkbp:patent |
gptkb:Gilead_Sciences
|
gptkbp:pregnancyCategory |
B1 (Australia)
N (US) |
gptkbp:routeOfAdministration |
oral
|
gptkbp:sells |
gptkb:Gilead_Sciences
|
gptkbp:sideEffect |
gptkb:anemia
nausea fatigue headache insomnia |
gptkbp:usedFor |
treatment of hepatitis C
|
gptkbp:bfsParent |
gptkb:DB09223
|
gptkbp:bfsLayer |
5
|