GFAP

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith gptkb:Alexander_disease
gliosis
gptkbp:category neurobiology
biomarker
cytoskeletal protein
gptkbp:discoveredIn 1971
gptkbp:encodedBy gptkb:GFAP_gene
gptkbp:expressedIn central nervous system
astrocytes
ependymal cells
radial glia
gptkbp:foundIn astrocytes
gptkbp:fullName gptkb:Glial_fibrillary_acidic_protein
gptkbp:function intermediate filament protein
structural support in central nervous system
gptkbp:gene gptkb:GFAP
gptkbp:HGNC_ID HGNC:4235
https://www.w3.org/2000/01/rdf-schema#label GFAP
gptkbp:locatedOnChromosome gptkb:17q21
gptkbp:molecularWeight ~50 kDa
gptkbp:mutationAssociatedWith gptkb:Alexander_disease
gptkbp:OMIM 137780
gptkbp:structure intermediate filament
gptkbp:UniProtID P14136
gptkbp:usedAs marker for astrocytes
gptkbp:usedIn neuroscience research
immunohistochemistry
gptkbp:bfsParent gptkb:Schwann_cell
gptkbp:bfsLayer 6