Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
nucleic acid secondary structure
|
| gptkbp:alsoKnownAs |
gptkb:G-quadruplex
|
| gptkbp:composedOf |
guanine-rich sequences
|
| gptkbp:detects |
X-ray crystallography
NMR spectroscopy circular dichroism spectroscopy |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:form |
four-stranded structure
|
| gptkbp:foundIn |
gptkb:gene
|
| gptkbp:hasTopology |
hybrid
parallel antiparallel |
| https://www.w3.org/2000/01/rdf-schema#label |
G4 motif
|
| gptkbp:involvedIn |
genome stability
regulation of gene expression telomere maintenance |
| gptkbp:motif |
G≥3NxG≥3NxG≥3NxG≥3
|
| gptkbp:recognizedBy |
G4-binding proteins
|
| gptkbp:relatedTo |
neurodegenerative diseases
human diseases viral genomes |
| gptkbp:stable |
gptkb:Hoogsteen_hydrogen_bonds
monovalent cations |
| gptkbp:studiedIn |
cancer research
|
| gptkbp:target |
small molecules
|
| gptkbp:bfsParent |
gptkb:Ras_domain
|
| gptkbp:bfsLayer |
6
|