|
gptkbp:instanceOf
|
gptkb:drug
fibrate
|
|
gptkbp:administeredBy
|
gptkb:tablet
capsule
|
|
gptkbp:approvedBy
|
gptkb:Australia
gptkb:Canada
gptkb:European_Union
gptkb:United_States
1975
|
|
gptkbp:ATCCode
|
C10AB05
|
|
gptkbp:bioavailability
|
variable, increased with food
|
|
gptkbp:brand
|
gptkb:Tricor
Antara
Fenoglide
Lipidil
Lipofen
Lofibra
Triglide
|
|
gptkbp:CASNumber
|
49562-28-9
|
|
gptkbp:category
|
antihyperlipidemic agent
|
|
gptkbp:contraindication
|
severe kidney disease
severe liver disease
gallbladder disease
|
|
gptkbp:developedBy
|
Laboratoires Fournier
|
|
gptkbp:drugClass
|
lipid-lowering agent
peroxisome proliferator-activated receptor agonist
|
|
gptkbp:eliminationHalfLife
|
20 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C20H21ClO4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fenofibrate
|
|
gptkbp:interactsWith
|
gptkb:warfarin
statins
bile acid sequestrants
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
PPAR-alpha agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
99%
|
|
gptkbp:riskFactor
|
muscular dystrophy
rhabdomyolysis
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
muscle pain
rash
gallstones
liver enzyme elevation
|
|
gptkbp:synonym
|
fenofibric acid ester
2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid, 1-methylethyl ester
|
|
gptkbp:usedFor
|
gptkb:familial_hypercholesterolemia
hypertriglyceridemia
|
|
gptkbp:bfsParent
|
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|