Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
bleeding disorder |
| gptkbp:affects |
coagulation
|
| gptkbp:alsoKnownAs |
gptkb:hemophilia_C
gptkb:Rosenthal_syndrome |
| gptkbp:causedBy |
mutation in F11 gene
|
| gptkbp:diagnosedBy |
prolonged activated partial thromboplastin time
low factor XI activity |
| gptkbp:firstDescribed |
Rosenthal et al.
|
| https://www.w3.org/2000/01/rdf-schema#label |
Factor XI deficiency
|
| gptkbp:ICD-10_code |
D68.2
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:OMIM |
612416
|
| gptkbp:prevalence |
higher in Ashkenazi Jewish population
|
| gptkbp:symptom |
easy bruising
menorrhagia postoperative bleeding prolonged bleeding after injury |
| gptkbp:treatment |
antifibrinolytic agents
fresh frozen plasma factor XI concentrate |
| gptkbp:bfsParent |
gptkb:FXI_deficiency
|
| gptkbp:bfsLayer |
8
|