Properties (74)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
ovarian cancer neuroblastoma lung cancer breast cancer prostate cancer head and neck cancers solid tumors chronic myeloid leukemia tumor progression gastrointestinal cancers Ewing sarcoma |
| gptkbp:bornIn |
certain cancers
|
| gptkbp:code |
transcription factor
|
| gptkbp:diedIn |
cell differentiation
|
| gptkbp:hasFunction |
transcriptional activation
DNA binding |
| gptkbp:hasPrograms |
FLI1_in_mice
|
| gptkbp:hasRole |
cell proliferation
cellular metabolism immune response wound healing embryonic development cellular response to stress neural development neurogenesis organogenesis vascular permeability tissue repair cell migration stem cell maintenance tissue homeostasis cell fate determination neural_crest_development |
| gptkbp:hasSubsidiary |
Friend leukemia integration 1
|
| https://www.w3.org/2000/01/rdf-schema#label |
FLI1 gene
|
| gptkbp:interactsWith |
chromatin remodeling complexes
ETS transcription factors Nuclear proteins other ETS factors transcriptional coactivators signaling_molecules |
| gptkbp:involvedIn |
cell cycle regulation
cell signaling pathways tumorigenesis cell survival angiogenesis cell adhesion cellular signaling pathways hematopoiesis immune cell differentiation vascular_development |
| gptkbp:is_evaluated_by |
placenta
skin adipose tissue bone marrow lymphoid tissues endothelial cells cardiovascular system |
| gptkbp:linkedTo |
genetic disorders
tumor microenvironment chromosomal abnormalities inflammatory responses metastasis neuroectodermal tumors sarcomas epithelial-mesenchymal transition 11q24.2 translocation events |
| gptkbp:locatedIn |
1990s
human chromosome 11 |
| gptkbp:partOf |
ETS family of transcription factors
|
| gptkbp:regulates |
gene expression
|