Statements (13)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
SARS-CoV-2 spike protein mutation
|
| gptkbp:aminoAcidChange |
Phenylalanine to Proline
|
| gptkbp:effect |
increases ACE2 binding affinity
increases immune escape |
| gptkbp:effectOnTherapeutics |
reduces effectiveness of some monoclonal antibodies
|
| gptkbp:firstReported |
2022
|
| gptkbp:foundIn |
gptkb:XBB.1.5
|
| https://www.w3.org/2000/01/rdf-schema#label |
F486P
|
| gptkbp:locatedIn |
receptor binding domain
|
| gptkbp:mutationAssociatedWith |
gptkb:SARS-CoV-2_spike_protein
|
| gptkbp:position |
486
|
| gptkbp:bfsParent |
gptkb:XBB.1.5_variant
|
| gptkbp:bfsLayer |
5
|