Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
villin-2
|
| gptkbp:associatedWith |
cancer progression
|
| gptkbp:encodedBy |
EZR gene
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
links plasma membrane to actin cytoskeleton
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ezrin
|
| gptkbp:interactsWith |
gptkb:actin
membrane proteins |
| gptkbp:locale |
microvilli
cell surface apical membrane of epithelial cells |
| gptkbp:locatedOnChromosome |
chromosome 6q25.3
|
| gptkbp:memberOf |
gptkb:ERM_protein_family
|
| gptkbp:molecularWeight |
~81 kDa
|
| gptkbp:phosphorylates |
threonine 567
|
| gptkbp:role |
signal transduction
cell migration cell adhesion |
| gptkbp:structure |
contains FERM domain
contains C-terminal actin-binding domain |
| gptkbp:UniProtID |
P15311
|
| gptkbp:bfsParent |
gptkb:ERM_(gene)
|
| gptkbp:bfsLayer |
7
|