|
gptkbp:instanceOf
|
gptkb:drug
alkaloid
Vasoconstrictor
|
|
gptkbp:ATCCode
|
G02AB03
|
|
gptkbp:CASNumber
|
60-79-7
|
|
gptkbp:category
|
Ergot alkaloid
Obstetric drug
Vasoconstrictor agent
|
|
gptkbp:chemicalClass
|
Ergoline alkaloid
|
|
gptkbp:contraindication
|
Hypertension
Ischemic heart disease
Pre-eclampsia
|
|
gptkbp:discoveredBy
|
Dudley T. Spivey
|
|
gptkbp:discoveredIn
|
1935
|
|
gptkbp:eliminationHalfLife
|
30 minutes
|
|
gptkbp:excretion
|
Urine
|
|
gptkbp:foundIn
|
gptkb:Ergot_fungus
|
|
gptkbp:hasMolecularFormula
|
C19H23N3O2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ergometrine
|
|
gptkbp:legalStatus
|
Prescription only
|
|
gptkbp:mechanismOfAction
|
Stimulates uterine smooth muscle contraction
|
|
gptkbp:meltingPoint
|
165°C
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:otherName
|
Ergonovine
|
|
gptkbp:pregnancyCategory
|
Contraindicated
|
|
gptkbp:PubChem_CID
|
8223
DB01253
|
|
gptkbp:riskFactor
|
gptkb:Ergotism
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Intramuscular
Intravenous
|
|
gptkbp:sideEffect
|
gptkb:Nausea
Headache
Hypertension
Vomiting
Vasoconstriction
|
|
gptkbp:solubility
|
Soluble in water
|
|
gptkbp:UNII
|
6T84R30KC1
|
|
gptkbp:usedFor
|
Prevention of postpartum hemorrhage
Treatment of postpartum hemorrhage
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
Yes
|
|
gptkbp:bfsParent
|
gptkb:Ergot_alkaloids
gptkb:Ergot_fungus
|
|
gptkbp:bfsLayer
|
7
|