Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Endogenous opioid peptide
Neuropeptide Peptide |
| gptkbp:aminoAcidSequence |
Tyr-Gly-Gly-Phe-Leu (Leu-enkephalin)
Tyr-Gly-Gly-Phe-Met (Met-enkephalin) |
| gptkbp:binds |
Delta-opioid receptor
Mu-opioid receptor Opioid receptors |
| gptkbp:category |
neurotransmitter
Neuromodulator |
| gptkbp:degradedBy |
Enkephalinase
|
| gptkbp:discoveredBy |
gptkb:John_Hughes
gptkb:Hans_Kosterlitz |
| gptkbp:discoveredIn |
1975
|
| gptkbp:effect |
gptkb:Euphoria
Analgesia Inhibition of neurotransmitter release |
| gptkbp:foundIn |
gptkb:Central_nervous_system
gptkb:Peripheral_nervous_system |
| gptkbp:function |
Pain modulation
Regulation of nociception |
| gptkbp:gene |
PENK
|
| https://www.w3.org/2000/01/rdf-schema#label |
Enkephalins
|
| gptkbp:location |
gptkb:Brain
Spinal cord |
| gptkbp:medicalUse |
Target for pain management research
|
| gptkbp:predecessor |
Proenkephalin
|
| gptkbp:relatedTo |
gptkb:Endorphins
gptkb:Dynorphins |
| gptkbp:type |
Leu-enkephalin
Met-enkephalin |
| gptkbp:bfsParent |
gptkb:Endorphins
|
| gptkbp:bfsLayer |
7
|