Endoplasmic Reticulum Degradation
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:alsoKnownAs |
ERAD
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:function |
protein quality control
removal of misfolded proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
Endoplasmic Reticulum Degradation
|
| gptkbp:involves |
gptkb:E3_ubiquitin_ligases
ubiquitin-proteasome system proteasomal degradation retrotranslocation |
| gptkbp:occurredIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:relatedTo |
neurodegenerative diseases
cystic fibrosis unfolded protein response protein misfolding diseases |
| gptkbp:studiedIn |
cell biology
|
| gptkbp:bfsParent |
gptkb:ERD
|
| gptkbp:bfsLayer |
7
|