Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Ionization technique
|
| gptkbp:abbreviation |
gptkb:ESI
|
| gptkbp:advantage |
High sensitivity
Minimal fragmentation |
| gptkbp:analyzes |
Polymers
Proteins Small molecules Nucleic acids Peptides |
| gptkbp:category |
Biochemistry
Physical chemistry Analytical chemistry |
| gptkbp:component |
Capillary needle
Desolvation gas Heated inlet High voltage power supply Nebulizing gas |
| gptkbp:enables |
Analysis of large biomolecules
Multiple charging of analytes Soft ionization |
| https://www.w3.org/2000/01/rdf-schema#label |
Electrospray Ionization
|
| gptkbp:introducedIn |
1980s
|
| gptkbp:inventedBy |
gptkb:John_B._Fenn
|
| gptkbp:limitation |
Limited to polar analytes
Matrix effects Suppression of ionization |
| gptkbp:NobelPrizeContribution |
2002 Nobel Prize in Chemistry
|
| gptkbp:operatesIn |
Atmospheric pressure
|
| gptkbp:processor |
Desolvation of droplets
Formation of charged droplets High voltage applied Release of gas-phase ions Sample dissolved in solvent Solution passed through capillary |
| gptkbp:produces |
Ions from solution
|
| gptkbp:relatedTo |
Atmospheric pressure chemical ionization
Matrix-assisted laser desorption/ionization |
| gptkbp:usedFor |
gptkb:Metabolomics
Proteomics Pharmaceutical analysis Time-of-flight mass spectrometry Tandem mass spectrometry Liquid chromatography Orbitrap mass spectrometry Quadrupole mass spectrometry |
| gptkbp:usedIn |
Mass spectrometry
|
| gptkbp:bfsParent |
gptkb:spectrometer
|
| gptkbp:bfsLayer |
5
|