Dupixent

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:administeredBy gptkb:physician
self-administration (with training)
gptkbp:approvedBy gptkb:FDA
gptkb:atopic_dermatitis
2017
asthma
chronic rhinosinusitis with nasal polyposis
eosinophilic esophagitis
gptkbp:ATCCode gptkb:D11AH05
gptkbp:brand gptkb:Dupixent
gptkbp:contraindication hypersensitivity to dupilumab
gptkbp:cost high (varies by country and insurance)
gptkbp:developedBy gptkb:Sanofi
gptkb:Regeneron_Pharmaceuticals
gptkbp:form pre-filled pen
pre-filled syringe
gptkbp:genericName gptkb:dupilumab
gptkbp:halfLife ~14-16 days
https://www.w3.org/2000/01/rdf-schema#label Dupixent
gptkbp:indication gptkb:prurigo_nodularis
chronic rhinosinusitis with nasal polyposis
eosinophilic esophagitis
moderate-to-severe asthma
moderate-to-severe atopic dermatitis
gptkbp:legalStatus prescription only
gptkbp:macromoleculeType gptkb:monoclonal_antibody
gptkbp:marketedIn gptkb:Australia
gptkb:Canada
gptkb:European_Union
gptkb:Japan
gptkb:United_States
gptkbp:mechanismOfAction IL-4 receptor alpha antagonist
gptkbp:patent gptkb:Sanofi
gptkb:Regeneron_Pharmaceuticals
gptkbp:pregnancyCategory N/A (consult physician)
gptkbp:prescribes adolescents
adults
children (age restrictions apply)
gptkbp:prescriptionRequired yes
gptkbp:routeOfAdministration subcutaneous injection
gptkbp:sideEffect conjunctivitis
injection site reactions
eye inflammation
oral herpes
gptkbp:storage refrigerated
gptkbp:target gptkb:interleukin-4
gptkb:interleukin-13
gptkbp:bfsParent gptkb:Sanofi
gptkbp:bfsLayer 5