|
gptkbp:instanceOf
|
gptkb:sedative
gptkb:antihistamine
gptkb:over-the-counter_medication
|
|
gptkbp:antidote
|
physostigmine (in severe cases)
|
|
gptkbp:ATCCode
|
R06AA09
|
|
gptkbp:availableOn
|
gptkb:Australia
gptkb:Canada
gptkb:United_Kingdom
gptkb:United_States
|
|
gptkbp:brand
|
gptkb:Unisom
Dozile
NyQuil (as ingredient)
Restavit
|
|
gptkbp:CASNumber
|
562-10-7
|
|
gptkbp:chemicalFormula
|
C17H22N2O·C4H6O4
|
|
gptkbp:contraindication
|
gptkb:glaucoma
urinary retention
severe liver disease
|
|
gptkbp:developedBy
|
gptkb:Merck_&_Co.
|
|
gptkbp:discoveredIn
|
1948
|
|
gptkbp:drugClass
|
ethanolamine antihistamine
|
|
gptkbp:eliminationHalfLife
|
10 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:legalStatus
|
OTC (over-the-counter) in US
|
|
gptkbp:mechanismOfAction
|
histamine H1 receptor antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
388.5 g/mol
|
|
gptkbp:overdoseSymptoms
|
gptkb:arrhythmia
coma
seizures
hallucinations
|
|
gptkbp:pregnancyCategory
|
Category A (Australia)
|
|
gptkbp:prescriptionStatus
|
non-prescription (most countries)
|
|
gptkbp:PubChem_CID
|
2298506
3033636
|
|
gptkbp:relatedTo
|
diphenhydramine
chlorpheniramine
|
|
gptkbp:riskFactor
|
anticholinergic toxicity in elderly
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
constipation
blurred vision
drowsiness
dry mouth
urinary retention
|
|
gptkbp:UNII
|
9445Z2A4LQ
|
|
gptkbp:usedFor
|
treatment of insomnia
relief of cold symptoms
relief of allergy symptoms
relief of hay fever symptoms
|
|
gptkbp:bfsParent
|
gptkb:Robitussin_Nighttime
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Doxylamine succinate
|