Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
sedative
antihistamine over-the-counter medication |
| gptkbp:antidote |
physostigmine (in severe cases)
|
| gptkbp:ATCCode |
R06AA09
|
| gptkbp:availableOn |
gptkb:Australia
gptkb:Canada gptkb:United_Kingdom gptkb:United_States |
| gptkbp:brand |
gptkb:Unisom
Dozile NyQuil (as ingredient) Restavit |
| gptkbp:CASNumber |
562-10-7
|
| gptkbp:chemicalFormula |
C17H22N2O·C4H6O4
|
| gptkbp:contraindication |
glaucoma
urinary retention severe liver disease |
| gptkbp:developedBy |
gptkb:Merck_&_Co.
|
| gptkbp:discoveredIn |
1948
|
| gptkbp:drugClass |
ethanolamine antihistamine
|
| gptkbp:eliminationHalfLife |
10 hours
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Doxylamine succinate
|
| gptkbp:legalStatus |
OTC (over-the-counter) in US
|
| gptkbp:mechanismOfAction |
histamine H1 receptor antagonist
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
388.5 g/mol
|
| gptkbp:overdoseSymptoms |
gptkb:arrhythmia
coma seizures hallucinations |
| gptkbp:pregnancyCategory |
Category A (Australia)
|
| gptkbp:prescriptionStatus |
non-prescription (most countries)
|
| gptkbp:PubChem_CID |
2298506
3033636 |
| gptkbp:relatedTo |
diphenhydramine
chlorpheniramine |
| gptkbp:riskFactor |
anticholinergic toxicity in elderly
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
constipation
blurred vision drowsiness dry mouth urinary retention |
| gptkbp:UNII |
9445Z2A4LQ
|
| gptkbp:usedFor |
treatment of insomnia
relief of cold symptoms relief of allergy symptoms relief of hay fever symptoms |
| gptkbp:bfsParent |
gptkb:Robitussin_Nighttime
|
| gptkbp:bfsLayer |
7
|