|
gptkbp:instanceOf
|
gptkb:antibiotic
gptkb:tetracycline_antibiotic
|
|
gptkbp:affiliatedWith
|
tetracyclines
|
|
gptkbp:ATCCode
|
gptkb:J01AA02
|
|
gptkbp:brand
|
gptkb:Adoxa
gptkb:Doryx
gptkb:Oracea
Atridox
Monodox
Periostat
Vibramycin
|
|
gptkbp:CASNumber
|
564-25-0
|
|
gptkbp:chemicalFormula
|
C22H24N2O8
|
|
gptkbp:contraindication
|
pregnancy
children under 8 years
|
|
gptkbp:discoveredBy
|
gptkb:Pfizer
|
|
gptkbp:discoveredIn
|
1967
|
|
gptkbp:eliminationHalfLife
|
18-22 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits protein synthesis
binds 30S ribosomal subunit
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
444.43 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
gptkb:Esophageal_cancer
nausea
vomiting
diarrhea
photosensitivity
tooth discoloration
|
|
gptkbp:synonym
|
doxycycline hyclate
doxycycline monohydrate
|
|
gptkbp:usedFor
|
gptkb:periodontitis
gptkb:rickettsial_infections
Lyme disease
cholera
anthrax
acne
urinary tract infections
chlamydia
gonorrhea
bacterial infections
respiratory tract infections
rosacea
malaria prophylaxis
syphilis (in penicillin allergy)
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Doxycycline
|