Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
tetracycline antibiotic |
| gptkbp:affiliatedWith |
tetracyclines
|
| gptkbp:ATCCode |
gptkb:J01AA02
|
| gptkbp:brand |
gptkb:Adoxa
gptkb:Doryx gptkb:Oracea Atridox Monodox Periostat Vibramycin |
| gptkbp:CASNumber |
564-25-0
|
| gptkbp:chemicalFormula |
C22H24N2O8
|
| gptkbp:contraindication |
pregnancy
children under 8 years |
| gptkbp:discoveredBy |
gptkb:Pfizer
|
| gptkbp:discoveredIn |
1967
|
| gptkbp:eliminationHalfLife |
18-22 hours
|
| gptkbp:excretion |
urine
feces |
| https://www.w3.org/2000/01/rdf-schema#label |
Doxycycline
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits protein synthesis
binds 30S ribosomal subunit |
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
444.43 g/mol
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
nausea
vomiting diarrhea photosensitivity Esophageal cancer tooth discoloration |
| gptkbp:synonym |
doxycycline hyclate
doxycycline monohydrate |
| gptkbp:usedFor |
gptkb:periodontitis
gptkb:rickettsial_infections Lyme disease cholera anthrax acne urinary tract infections chlamydia gonorrhea bacterial infections respiratory tract infections rosacea malaria prophylaxis syphilis (in penicillin allergy) |
| gptkbp:WHOModelListOfEssentialMedicines |
yes
|
| gptkbp:bfsParent |
gptkb:Zentiva
|
| gptkbp:bfsLayer |
7
|