Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
complication of diabetes mellitus |
| gptkbp:affects |
gptkb:kidney
|
| gptkbp:cause |
gptkb:anemia
chronic kidney disease hyperkalemia fluid overload end-stage renal failure |
| gptkbp:complication |
gptkb:cardiovascular_disease
peripheral neuropathy retinopathy |
| gptkbp:diagnosedBy |
urine albumin test
glomerular filtration rate measurement serum creatinine test |
| gptkbp:firstDescribed |
Kimmelstiel and Wilson
|
| gptkbp:hasEpidemiology |
affects 20-40% of diabetic patients
leading cause of end-stage renal disease worldwide |
| https://www.w3.org/2000/01/rdf-schema#label |
Diabetic Nephropathies
|
| gptkbp:ICD-10_code |
E10.2
E11.2 |
| gptkbp:MeSH_ID |
D003937
|
| gptkbp:pathology |
basement membrane thickening
glomerulosclerosis mesangial expansion |
| gptkbp:prevalence |
gptkb:type_2_diabetes
type 1 diabetes |
| gptkbp:prevention |
smoking cessation
blood pressure management tight glycemic control lipid control |
| gptkbp:prognosis |
improved with early detection and management
progressive without intervention |
| gptkbp:riskFactor |
hypertension
genetic predisposition long duration of diabetes poor glycemic control |
| gptkbp:stageName |
end-stage renal disease
macroalbuminuria microalbuminuria |
| gptkbp:symptom |
edema
hypertension proteinuria |
| gptkbp:treatment |
gptkb:angiotensin_receptor_blockers
ACE inhibitors blood pressure control glycemic control dietary protein restriction |
| gptkbp:bfsParent |
gptkb:D003700
|
| gptkbp:bfsLayer |
7
|