|
gptkbp:instanceOf
|
gptkb:chelation_agent
gptkb:drug
|
|
gptkbp:administeredBy
|
intramuscular injection
subcutaneous injection
intravenous injection
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
gptkb:V03AC01
|
|
gptkbp:brand
|
gptkb:Desferal
|
|
gptkbp:CASNumber
|
70-51-9
|
|
gptkbp:category
|
gptkb:World_Health_Organization_essential_medicine
gptkb:iron_chelator
gptkb:antidote
|
|
gptkbp:chemicalFormula
|
C25H48N6O8
|
|
gptkbp:contraindication
|
severe renal impairment
hypersensitivity to desferrioxamine
|
|
gptkbp:discoveredBy
|
Hans Theil
|
|
gptkbp:elimination_route
|
urine
bile
|
|
gptkbp:KEGGID
|
D00110
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
binds free iron
forms ferrioxamine complex
|
|
gptkbp:molecularWeight
|
560.684 g/mol
|
|
gptkbp:origin
|
produced by Streptomyces pilosus
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
2973
2868
CHEMBL1200697
DB00552
|
|
gptkbp:routeOfAdministration
|
parenteral
|
|
gptkbp:sideEffect
|
vision problems
hearing loss
allergic reactions
growth retardation
lung problems
|
|
gptkbp:UNII
|
J06Y7MXW4D
|
|
gptkbp:usedFor
|
gptkb:thalassemia_major
treatment of aluminum toxicity
sideroblastic anemia
acute iron poisoning
transfusional hemosiderosis
treatment of iron overload
|
|
gptkbp:bfsParent
|
gptkb:Deferoxamine
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
Desferrioxamine
|